欧洲10年的研究：辅酶Q10已被证实对心力衰竭患者有好处
CoQ10 Proven Benefits In Heart Failure Patients
By Bradley Tompkins
CoQ10已被证实对心力衰竭患者有好处
欧洲心脏衰竭杂志发表了迄今为止关于辅酶Q10最有力的研究之一的数据。
这项为期10年的研究最终表明，补充CoQ10可以显著提高即使是最严重的心力衰竭患者的生存率，同时从根本上减少住院率。
这项新的研究表明，补充CoQ10可以恢复中重度心力衰竭患者CoQ10水平的不足，延长寿命，提高生活质量。
这项长达10年的研究得出了令人信服的结果:每天服用100毫克CoQ10三次的患者……
死于心力衰竭的可能性要小得多，
死于任何原因的可能性不到一半，而且
与对照组相比，在研究期间发生重大不良心脏事件的可能性是对照组的一半
仅仅3个月的补充后，研究人员发现了一种趋势，即过度工作的心肌细胞释放出的一种反映心力衰竭严重程度的血液标志物水平下降。两年后，接受治疗的患者中改善心功能测量的患者明显多于接受安慰剂治疗的患者。
这项令人印象深刻的研究展示了CoQ10如何提供重要的心脏健康益处，以及它对心脏病人的重要性。理想情况下，心脏病学的实践将很快包括CoQ10，作为他们改善心衰患者生活方案的一部分。
心脏生物能学
大多数人听说过心力衰竭，但很少有人真正了解它是什么。
与大多数人的想法相反，心力衰竭并不意味着心脏停止跳动。相反，当心脏不能泵出足够的血液来维持其他器官的正常功能时，就会发生心力衰竭。
你的心是你身体里最努力工作的器官之一;它从不需要休息。在你的一生中，你的心脏每秒钟都会收缩和放松一次以上，提供你身体其他器官所依赖的血液流动。
这么大的努力需要稳定的能源供应。为了达到最佳的功能- - - - - - - - - -你的心脏需要能够从它的燃料(主要是脂肪酸和葡萄糖)中有效地获得能量，并且不浪费。
为了支持这项任务，你的线粒体从食物中释放出稳定的能量。这就是所谓的生物能学。但是线粒体并不是单独起作用的。就像清洁燃烧的汽车引擎比老化的引擎更省油、更耐用一样，线粒体也需要帮助保持顶级的效率和性能。
CoQ10对心脏维持足够的能量管理至关重要。当CoQ10水平下降时，组织燃烧燃料效率低下，最终产生氧化损伤，最终失去功能。当心脏肌肉失去能量效率时，可能会发生心力衰竭
研究表明，心力衰竭患者的CoQ10水平较低，且水平越低，心力衰竭越严重。事实上，CoQ10水平较低的心力衰竭患者的死亡风险比CoQ10水平较高的患者高两倍。
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CoQ10 Proven Benefits In Heart Failure Patients
April 2014
By Bradley Tompkins
CoQ10 Proven Benefits In Heart Failure Patients
The European Journal of Heart Failure has published data from one of the most robust studies to date on coenzyme Q10.
This ten year study conclusively showed that CoQ10 supplementation significantly improves survival for even the most severe heart failure patients while radically reducing incidences of hospitalization.1
This new study shows that CoQ10 supplementation can restore deficient CoQ10 levels in patients with moderate-to-severe heart failure, extend lifespan, and improve quality of life.1
The compelling results from this 10-year-long study found that patients who took 100 mg of CoQ10 three times daily were…
Significantly less likely to die from heart failure,
Less than half as likely to die from any cause at all, and
Half as likely to have a major adverse cardiac event during the study period, compared with control subjects.1
After only three months of supplementation, the researchers detected a trend towards reduced levels of a blood marker of heart failure severity that is released from over-worked heart muscle cells.1,2 At two years, significantly more treated patients had improved measurements of heart function than did placebo recipients.1
This impressive study demonstrates how CoQ10 offers important heart health benefits and how essential it is to cardiac patients. Ideally, the practice of cardiology will soon include CoQ10 as part of their protocol to improve the lives of those living with heart failure.
Cardiac Bioenergetics
Most people have heard of heart failure, but few understand what it really is.
Contrary to what most people might think, heart failure does not mean that the heart stops beating. Rather, heart failure occurs whenever the heart is unable to pump enough blood to sustain normal function in other organs.3
Your heart is one of the hardest-working organs in your body; it literally never takes a rest. Beat after beat, hour after hour, day after day, for your entire life, your heart contracts and relaxes a little more than once per second, providing the blood flow that every other organ in your body relies on.
That much effort requires a steady supply of energy. And to perform at optimal function—literally without missing a beat—your heart needs to be able to derive that energy from its fuel (primarily fatty acids and glucose) efficiently and with little waste.4-6
In order to support this task, your mitochondria pump out a steady supply of energy derived from food. This is called bioenergetics.7 But your mitochondria don’t work alone. Just as a clean-burning automobile engine is more fuel-efficient and lasts longer than an out-of-tune one, the mitochondria need help maintaining top-level efficiency and performance.
CoQ10 is essential for the heart to maintain sufficient energy management.1,8 But when CoQ10 levels decline, tissues burn fuel inefficiently, eventually producing oxidative damage and ultimately losing their function. When the heart muscle loses its fuel efficiency, heart failure may occur.4,9
Research has shown that CoQ10 levels are lower in patients with heart failure and the lower the levels, the more severe the failure.8,10,11 In fact, heart failure patients with lower CoQ10 levels have up to a two-fold risk of dying compared to those with higher levels.12
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