伦敦大学 鱼油 亚麻籽可以预防和治疗神经损伤

Omega-3 fatty acids could prevent and treat nerve damage, research suggests

来源:伦敦大学玛丽女王学院

一项新的研究表明,鱼油中所含的Omega-3脂肪酸有保护神经免受伤害和帮助神经再生的潜力。

伦敦大学玛丽皇后学院的一项研究表明,鱼油中所含的omega-3脂肪酸有保护神经免受伤害和帮助神经再生的潜力。当神经因意外或受伤而受损时,患者会感到疼痛、虚弱和肌肉瘫痪,这可能导致他们残疾,康复率很低。

 

亚麻籽油,​鱼油中所含的omega-3脂肪酸有保护神经免受伤害和帮助神经再生的潜力。

 

本周发表在《神经科学杂志》(Journal of Neuroscience)上的一项新研究表明,omega-3脂肪酸在加快神经损伤的恢复过程中可能扮演着重要角色。

这项研究集中在周围神经细胞上。外周神经是在大脑、脊髓和身体其他部位之间传递信号的神经。

这些神经有再生的能力,但尽管外科技术进步,病人通常只有在损伤很小的时候才有好的恢复。

Omega-3脂肪酸对人体的正常生长和发育至关重要,它的健康益处已被广泛研究。因为人体不能制造欧米伽-3脂肪酸,所以它们必须被食用在油性鱼类等食物中。

在这项新的研究中,研究人员首先观察了分离的老鼠神经细胞。他们通过拉伸细胞或使其缺氧来模拟由意外或损伤引起的损伤类型。这两种类型的损伤都杀死了大量的神经细胞,但细胞中富含omega-3脂肪酸使它们得到了显著的保护并减少了细胞死亡。

 

细胞中富含omega-3脂肪酸能保护神经

 

接下来,研究人员研究了小鼠的坐骨神经。他们发现,高水平的omega-3脂肪酸有助于小鼠更快更充分地从坐骨神经损伤中恢复,而且它们的肌肉在神经损伤后不太可能浪费。

这项研究是由巴茨和伦敦医学院的神经科学教授Adina Michael-Titus领导的一个小组进行的,她是伦敦大学玛丽女王学院神经科学与创伤中心神经创伤和神经变性研究小组的组长。

她解释说:“我们之前的研究表明,这些脂肪酸可以对一些神经系统疾病产生有益的影响。这项新研究表明,它们在治疗周围神经损伤方面也有作用。

 

欧米茄-3脂肪酸可以保护受损的神经细胞

 

“还需要做更多的工作,但我们的研究表明欧米茄-3脂肪酸可以保护受损的神经细胞,这是神经系统成功恢复的关键第一步。”

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资料由伦敦大学玛丽皇后学院提供。

Omega-3 fatty acids could prevent and treat nerve damage, research suggests

Date:

January 11, 2012

Source:

Queen Mary, University of London

Summary:

Omega-3 fatty acids, which are found in fish oil, have the potential to protect nerves from injury and help them to regenerate, new research suggests.

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FULL STORY

Research from Queen Mary, University of London suggests that omega-3 fatty acids, which are found in fish oil, have the potential to protect nerves from injury and help them to regenerate. When nerves are damaged because of an accident or injury, patients experience pain, weakness and muscle paralysis which can leave them disabled, and recovery rates are poor.

The new study, published this week in the Journal of Neuroscience, suggests that omega-3 fatty acids could play a significant role in speeding recovery from nerve injury.

The study focused on peripheral nerve cells. Peripheral nerves are the nerves which transmit signals between the brain and spinal cord, and the rest of the body.

These nerves have the ability to regenerate but, despite advances in surgical techniques, patients usually only have good recovery when their injury is minor.

Omega-3 fatty acids are vital for the body's normal growth and development and have been widely researched for their health benefits. Because the body cannot manufacture omega-3 fatty acids, they have to be consumed in foods such as oily fish.

In the new study, researchers first looked at isolated mouse nerve cells. They simulated the type of damage caused by accident or injury, by either stretching the cells or starving them of oxygen. Both types of damage killed a significant number of nerve cells but enrichment with omega-3 fatty acids in cells gave them significant protection and decreased cell death.

Next the researchers studied the sciatic nerves of mice. They found that a high level of omega-3 fatty acids helped mice to recover from sciatic nerve injury more quickly and more fully, and that their muscles were less likely to waste following nerve damage.

The research was carried out by a group led by Adina Michael-Titus, Professor of Neuroscience at Barts and The London Medical School and lead of the Neurotrauma and Neurodegeneration group in the Centre for Neuroscience and Trauma, Queen Mary, University of London.

She explained: "Our previous research has shown that these fatty acids could have beneficial effects in a number of neurological conditions. This new study suggests that they could also have a role in treating peripheral nerve injuries.

"More work is needed but our research indicates that omega-3 fatty acids can protect damaged nerve cells, which is a critical first step in a successful neurological recovery."

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Materials provided by Queen Mary, University of London. Note: Content may be edited for style and length.

Omega-3 fatty acids could prevent and treat nerve damage, research suggests -- ScienceDaily  https://www.sciencedaily.com/releases/2012/01/120111103856.htm