欧洲医生在心脏病发作后开鱼油处方 降低死亡率和突然死亡率
European Doctors Prescribe Fish Oil After Heart Attacks
欧洲医生在心脏病发作后开鱼油处方 降低死亡率和突然死亡率
《纽约时报》(New York Times)最近的一篇报道称,尽管欧洲心脏病患者通常会服用鱼油,但在美国,这种做法很少被遵守。
在许多研究中,富含omega-3脂肪酸的鱼油被证明可以提高心脏病发作后的存活率,降低致命的心律不齐。然而,在美国,心脏病患者很少服用欧米伽-3脂肪酸,尽管他们通常会接受更昂贵的侵入性治疗,比如降胆固醇药物和植入式除颤器。
欧洲医生在心脏病发作后开鱼油处方 降低死亡率和突然死亡率
亚特兰大埃默里大学的预防心脏病专家特里·雅各布森博士告诉《纽约时报》,“尽管数据支持omega-3脂肪酸,但大多数心脏病专家并没有提供-3脂肪酸——这是一个真正的脱节。他们在接受治疗方面进展缓慢。
据《纽约时报》报道,全球心脏护理领域的广泛差异凸显了制药公司在传播医疗信息方面的决定性作用。由于处方鱼油在美国没有获得预防心脏病的许可,制药公司可能不会为此目的在法律上推广它,而医生通常也不会向患者推荐它。
根据最近发表在美国家庭医学委员会期刊上的一项研究,只有17%的家庭医生会给他们的病人开鱼油,包括那些心脏病发作的病人。作者总结说,有必要“提高对这一重要建议的认识”。
在十多年前进行的一项具有里程碑意义的鱼油研究中,GISSI研究小组的意大利研究人员在11000名患者心脏病发作后,每天给他们服用1克处方鱼油。三年后,与对照组相比,死亡人数减少了20%,突然死亡人数减少了40%。到2004年,包括西班牙、法国和英国在内的几乎所有欧洲国家的医疗监管机构都批准了用于心脏病患者的处方鱼油。美国心脏病学院现在建议冠状动脉疾病患者将-3脂肪酸的摄入量增加到每天1克。
OMEGA-3 脂肪酸的保健作用
米兰马里奥·内格里研究所(Mario Negri Institute)的研究员玛丽亚·弗兰索西(Maria Franzosi)博士告诉《泰晤士报》,使用鱼油“在意大利非常流行,我认为部分原因是这个国家有很多心脏病专家参与了这项研究,并且知道研究结果”。在其他国家,这可能更难实现,因为医生认为这只是一种饮食干预。
关于鱼油的研究在欧洲继续得到发展。GISSI研究小组的研究人员目前正在进行两项主要试验,以检验鱼油对心律失常患者和心力衰竭患者的影响。
资料来源
Rosenthal E. In Europe it’s fish oil after heart attacks, but not in US. New York Times. October 3, 2006.
主要概念:鱼油,欧洲医生,心脏病
https://s.click.taobao.com/tS8sKNw
European Doctors Prescribe Fish Oil After Heart Attacks
Although heart-attack survivors in Europe are routinely prescribed fish oil, this practice is rarely followed in the United States, according to a recent report in the New York Times.
In numerous studies, fish oil rich in omega-3 fatty acids has been shown to improve survival after heart attacks and to reduce fatal heart rhythms. In the US, however, heart attack victims are rarely given omega-3 fatty acids, though they are routinely prescribed more expensive and invasive treatments, such as cholesterol-lowering drugs and implantable defibrillators.
Dr. Terry Jacobson, a preventive cardiologist at Emory University in Atlanta, told the Times, “Most cardiologists here are not giving omega-3s, even though the data support it—there’s a real disconnect. They have been very slow to incorporate the therapy.”
Wide variations in cardiac care around the world underscore the decisive role that drug companies play in disseminating medical information, according to the Times report. Because prescription fish oil is not licensed to prevent heart disease in the US, drug companies may not legally promote it for that purpose, and doctors routinely fail to recommend it to their patients.
According to a recent study published in the Journal of the American Board of Family Medicine, only 17% of family doctors were likely to prescribe fish oil to their patients, including those who had suffered a heart attack. The authors concluded that there was a great need to “improve awareness of this important advice.”
In a landmark study of fish oil conducted more than a decade ago, Italian researchers from the GISSI Group gave 11,000 patients 1 gram of prescription fish oil a day after they had suffered a heart attack. After three years, the number of deaths was reduced by 20% and the number of sudden deaths by 40% compared to a control group. By 2004, medical regulatory authorities in almost all European countries, including Spain, France and Britain, had approved prescription fish oil for use in heart attack patients. The American College of Cardiology now advises patients with coronary artery disease to increase their consumption of omega-3 acids to 1 gram a day.
Dr. Maria Franzosi, a researcher at the Mario Negri Institute in Milan, told the Times that the use of fish oil “is very popular here in Italy, I think partly because so many cardiologists in this country participated in the studies and were aware of the results. In other countries, uptake may be harder because doctors think of it as just a dietary intervention.”
Research on fish oil continues to gain momentum in Europe. Researchers from the GISSI Group are now conducting two major trials to examine fish oil’s effects in patients with abnormal heart rhythms and in patients with heart failure.
Source
Rosenthal E. In Europe it’s fish oil after heart attacks, but not in US. New York Times. October 3, 2006.
Key concepts: Fish oil, European Doctors, heart attack
http://www.rejuvenation-science.com/research-news/omega-3-fish-oil-1/n-fish-oil-heart-attack