高压氧治疗原位肝移植术后肝动脉血栓形成及功能性胆汁淤积的疗效

Therapeutic Effect of Hyperbaric Oxygen in Hepatic Artery Thrombosis and Functional Cholestasis After Orthotopic Liver Transplantation

　

特别肝移植单元-放射学部门，里贝奥·普雷托医学院，圣保罗大学，巴西圣保罗。
 
摘要
在术后并发症中，高达10%的成人原位肝移植可发生肝动脉血栓形成，需要在30天内再次进行肝动脉血栓形成干预。原发性移植物功能障碍，可发生在多达30%的病例，是另一个潜在的并发症，虽然可逆，但死亡率较高。高压氧治疗是一种有效的组织氧合治疗方式，在临床应用越来越广泛。我们在此报告两位高压氧治疗对原位肝移植术后并发症有很大帮助的病人:一位有肝动脉血栓形成，另一位有原发性移植物功能障碍。两例患者在开始高压氧治疗后均表现出临床快速恢复，肝和小管酶逐渐减少。

　

　

Liver transplantation

Special Liver Transplantation Unit - Sector of Radiology, Ribeirão Preto School of Medicine, University of São Paulo, São Paulo, Brazil.

 

https://doi.org/10.1016/j.transproceed.2006.06.062Get rights and content

Abstract

Among the postoperative complications, hepatic artery thrombosis can occur in up to 10% of adult orthotopic liver transplants and intervention is indicated when this occurs within 30 days by retransplantation. Primary graft dysfunction, which can occur in up to 30% of the cases and is another potential complication, although reversible, has a relatively high mortality rate. Hyperbaric therapy, an efficient mode of tissue oxygenation, is being used in an increasing number of clinical situations. We report here two cases where hyperbaric oxygen therapy greatly benefited patients with complications after orthotopic liver transplantation: one with hepatic artery thrombosis and the other with primary graft dysfunction. Both patients showed rapid clinical recovery with gradual reduction of liver and canalicular enzymes soon after commencing hyperbaric oxygen therapy.

 

Therapeutic Effect of Hyperbaric Oxygen in Hepatic Artery Thrombosis and Functional Cholestasis After Orthotopic Liver Transplantation - ScienceDirect  https://www.sciencedirect.com/science/article/pii/S0041134506006841