肝硬化患者肝动脉、门静脉氧含量及提取

Hepatic arterial and portal venous oxygen content and extraction in liver cirrhosis

通过对肝硬化患者肝动脉、肝静脉血、门静脉静脉血中氧含量的测定，评价肝硬化患者肝供氧情况及肝提取氧情况。肝硬化患者门静脉氧含量差异在正常范围内，肝动脉和门静脉氧含量低于对照组。肝硬化患者肝静脉血氧含量正常。脾静脉的氧张力和饱和度始终高于门静脉系统的其他分支。肝动脉主要供氧，肝硬化时动脉氧提取正常。此外，肝硬化患者吸入氧气时动脉提取无变化。肝硬化门脉静脉血氧的提取减少，吸氧增加。这些发现表明通过肝动脉和肺静脉氧供应的相互关系，肝氧的自动调节。

Hepatic arterial and portal venous oxygen content and extraction in liver cirrhosis

We examined the oxygen content in the hepatic arterial, hepatic venous and portal venous blood to evaluate the oxygen supply to the liver and hepatic oxygen extraction in cirrhosis. The arterial‐portal venous difference of the oxygen content was within the normal range in cirrhosis patients, although the oxygen content of the hepatic artery and portal vein was lower than in the control patients. The hepatic venous oxygen content was normal in the cirrhosis patients. The oxygen tension and saturation were always higher in the splenic vein than in the other branches of the portal system. Oxygen was supplied chiefly by the hepatic artery, and arterial oxygen extraction was normal in cirrhosis. In addition, there was no change in arterial extraction during oxygen inhalation by cirrhosis patients. Portal venous oxygen extraction was decreased in cirrhosis and was increased by oxygen inhalation. These findings indicate the autoregulation of hepatic oxygen through a mutual relationship between the hepatic arterial and the portovenous oxygen supply.

https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1600-0676.1993.tb00602.x