维生素C:实验室测试表明有抗艾滋病毒(HIV)作用
VITAMIN C: LABORATORY TESTS INDICATE ANTIVIRAL EFFECT
位于加州帕洛阿尔托的莱纳斯鲍林科学与医学研究所的一系列实验室测试发现抗坏血酸(维生素C)可以减少培养的人类淋巴细胞中HIV病毒的生长,其浓度对细胞无害。这项实验研究由Steve Harakeh博士和Raxit J. Jariwalla博士共同完成,发表在美国国家科学院学报9月刊上;研究结果也在9月11日于马里兰州贝塞斯达举行的“抗坏血酸:生物功能与癌症关系Ascorbic Acid: Biological Functions and Relation to Cancer”国际研讨会上公布。
这项研究是广泛的,很难总结,但它显示了措施导致HIV的实质性减少。
病毒活性(p24,逆转录酶,合胞体形成)在浓度为25 ~ 150 mcg/ml时对细胞无毒性,浓度越高,效果越好。
需要多少维生素C才能达到血清中的这些水平?这项研究没有测量血液水平,但发表的论文引用了其他人的测量数据。一位研究人员发现口服10克维生素C后血浆浓度可达到28.91 微克/毫升;
另一项研究发现,每天静脉输注50克维生素c可使血浆最高水平达到796微克/毫升。
VITAMIN C: LABORATORY TESTS INDICATE ANTIVIRAL EFFECT
A series of laboratory tests at the Linus Pauling Institute of Science and Medicine in Palo Alto, California found that ascorbate (vitamin C) reduced the growth of HIV in cultured human lymphocytes, in concentrations not harmful to the cells. The experimental study, conducted by Steve Harakeh, Ph.D., and Raxit J. Jariwalla, Ph.D., appears in the September issue of the Proceedings of the National Academy of Sciences, USA; results were also presented September 11 at “Ascorbic Acid: Biological Functions and Relation to Cancer,” an international symposium sponsored by the U.S. National Cancer Institute, and National Institute of Diabetes and Digestive and Kidney Diseases, in Bethesda, Maryland. The study is extensive and hard to summarize, but it showed a substantial reduction in measures
of viral activity (p24, reverse transcriptase, and syncytia formation) without toxicity to cells at concentrations of 25 to 150 mcg/ml, with the higher concentrations working better.
How much vitamin C would be needed to reach these levels in blood serum? This study did not measure blood levels, but the published paper cited measurements by others. One researcher
found an average blood level of 28.91 mcg/ml after oral use of 10 grams of vitamin C. Another found that intravenous infusion of 50 grams a day led to a peak plasma level of 796 mcg/ml.
VITAMIN C: LABORATORY TESTS INDICATE ANTIVIRAL EFFECT - AIDS Information, Education, Action, AwarenessAIDS Information, Education, Action, Awareness http://www.aids.org/2010/10/vitamin-c-laboratory-tests-indicate-antiviral-effect/