How Does Turmeric Impact Hepatitis?
2007年1月发表在《临床免疫学杂志》(Journal of Clinical Immunology)上的一篇文章指出，姜黄素在免疫系统细胞中显示出免疫调节活性。根据G.C. Jaggetia和B.B. Aggerwal的研究，“姜黄素对关节炎、过敏、哮喘、动脉粥样硬化、心脏病、阿尔茨海默病、糖尿病和癌症的有益作用可能部分归功于它调节免疫系统的能力。”潜在的姜黄素已经被证明是一种免疫调节剂，它是一种合理的，便宜的，所有的自然选择来帮助战胜肝炎。
以色列的一项研究发现，姜黄素可以保护大鼠不受硫代乙酰胺引起的肝硬化的影响。研究人员得出结论，通过抑制肿瘤坏死因子alpha (TNF-alpha)、肝星状细胞激活和collage alpha 1 (I)基因表达，姜黄素显示出合理的延缓肝硬化发展的能力。
How Does Turmeric Impact Hepatitis?
Nicole Cutler, L.Ac., MTCM, Dipl. Ac. (NCCAOM)®
August 26, 2013
The focus of a wide range of clinical studies, curcumin has repeatedly demonstrated liver benefits. While more research is called for, there remains no concrete evidence that this herb specifically changes the outcome of viral hepatitis. However, the information gathered thus far overwhelmingly supports adding curcumin to a liver health routine.
Curcumin (Curcuma longa) is the source of the spice turmeric, and is used in curries and other spicy dishes from India, Asia and the Middle East. Curcumin is what gives the curry its characteristic bright yellow color and strong taste. Holding respected positions in Ayuverdic Medicine and Traditional Chinese Medicine, turmeric is an herb that these time-honored institutions consider able to cleanse the body and invigorate congealed blood. An increasing amount of attention is being paid to turmeric’s health benefits, as modern-day scientists recognize its anti-inflammatory properties and find a growing list of illnesses that its active ingredient benefits.
A Cholesterol Advantage
Several studies have reported that curcumin improves cholesterol ratio, which has a direct benefit on heart and liver health:
A controlled trial in India administered 500 mg of curcumin for seven days at Amala Cancer Research Centre in India. Researchers found that 29 percent of participants experienced an increase in good cholesterol (HDL), while 11.6 percent of participants had a reduction of total cholesterol. Additionally, lipid peroxidation, the process by which cells incur damage, was found to be reduced by 33 percent.
Another study by the Faculty of Pharmacy at the University of Granada reported that curcumin was effective in inhibiting LDL oxidation and lowering LDL cholesterol and triglycerides.
According to the latest research, curcumin reduces cholesterol by interfering with intestinal cholesterol uptake, increasing the conversion of cholesterol into bile acids, and subsequently increasing the excretion of those bile acids.
Another 2000 study shows that a daily oral administration of curcumin extract significantly decreases LDL and apo B (a leading heart disease risk factor) and increases the HDL and apo A of healthy subjects.
Whenever cholesterol ratio improves (HDL is raised, or LDL, triglycerides or total cholesterol are lowered), the strain on the heart and liver is reduced. For a person with chronic hepatitis, minimizing any additional strain on the liver is crucial for assuring longevity.
An Immune System Ally
Since a strong immune system is a person’s best hope for defeating infection with any virus – including hepatitis – immune modulators are consistently being sought. Immune modulation is an emerging field in the medical treatment of viral infections. By introducing an agent into the body that boosts specific areas of the immune system, immune modulators likely lead to an increase in ability to fight off viral infections. While pharmaceutical companies are racing to manufacture the best immune modulator for the different hepatitis viruses, naturally occurring modulators are much cheaper and typically free of side effects.
Researchers are examining curcumin as a possible immune stimulator that can boost these different cells of the immune system:
Natural killer cells
As reported in the January 2007 edition of Journal of Clinical Immunology, curcumin demonstrates immune modulation activity in immune system cells. According to researchers G.C. Jaggetia and B.B. Aggerwal, “curcumin’s reported beneficial effects in arthritis, allergy, asthma, atherosclerosis, heart disease, Alzheimer’s disease, diabetes, and cancer might be due in part to its ability to modulate the immune system.” The potential curcumin has demonstrated as an immune modulator renders it a logical, inexpensive, all natural choice for helping defeat hepatitis.
Even when burdened with liver disease, protecting the liver from acquiring any further damage is the best way to live a long life. Scientists confirmed that curcumin protects the liver by acting as an anti-inflammatory agent:
Protects Against Acute Liver Damage – A Mexican study found that livers of rats treated with curcumin were protected from liver damage induced by carbon tetrachloride. Researchers concluded that by inhibiting NF-kappaB activation and thus inhibiting the production of pro-inflammatory cytokines, curcumin protected against acute liver damage.
Protects Against Liver Cirrhosis – An Israeli study found that curcumin protected rats against the development of liver cirrhosis as induced by thioacetamide. Researchers concluded that by inhibiting the expression of tumor necrosis factor alpha (TNF-alpha), hepatic stellate cell activation and collage alpha 1 (I) gene expression, curcumin demonstrated a reasonable ability to slow the development of liver cirrhosis.
With documentation that this herb minimizes inflammation and slows cirrhosis, curcumin has the ability to quell potential damage from hepatitis.
As the main ingredient in curry, many mistakenly assume that large quantities of turmeric are completely safe. While traditionally safe at low doses, excessive intake of curcumin may irritate the stomach lining. People who have been diagnosed with gallstones, have a bile obstruction or are pregnant should only commence with supplementation under the guidance of a qualified practitioner. Additionally, curcumin has a blood thinning effect; therefore it can be dangerous if combined with blood thinning medications. If taking a blood thinner such as coumadin, warfarin or aspirin, supervision is required for curcumin supplementation.
As long as you heed its cautions and double-check your intent with a physician, supplementing with curcumin can offer a person with hepatitis great benefit. Ranging from its ability to improve cholesterol ratios, promise as an immune modulator and demonstration as a liver protector, curcumin is emerging as an ideal herbal supplement for a person living with hepatitis.